Chlamydia trachomatis tissue tropism

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August undefined, 2024

WebClinical importance. Chlamydia trachomatis is an important pathogen of the genital tract in both men and women. Infection can result in ‘non-specific’ or non-gonococcal urethritis, … WebChlamydial epidemiology: global burden of disease. Chlamydia trachomatis is an obligate intracellular bacterial pathogen primarily of human conjunctival and urogenital columnar epithelial cells. 1,2 Infections of cells at these mucosal surfaces with tissue-tropic oculogenital serovars of C. trachomatis can result in trachoma (ocular serovars A, B, …

Genomic Analysis of MSM Rectal Chlamydia trachomatis

WebAug 1, 2002 · HeLa cells were infected with C. trachomatis serovar L2, D, A, and I EBs at an m.o.i. of 3–5 IFU cell 1 or left uninfected (mock) in MEM, 10% dialyzed FCS … WebChlamydia trachomatis is the most prevalent sexually transmitted bacterium worldwide and the causative agent of trachoma. Its strains are classified according to their ompA genotypes, which are strongly linked to differential tissue tropism and disease outcomes [ocular disease, urogenital disease and lymphogranuloma venereum (LGV)]. While the … portland or zep code

Genetic Variation in Chlamydia trachomatis and Their Hosts

WebApr 5, 2024 · The most common species of the genus Chlamydia that colonizes the human host causing disease is Chlamydia trachomatis . ... J. H. Carlson et al., “Molecular basis defining human Chlamydia trachomatis tissue tropism. A possible role for tryptophan synthase,” The Journal of Biological Chemistry, vol. 277, no. 30, pp. 26893–26903, 2002. WebApr 7, 2015 · Here we investigate genetic differences on the whole-genome level that are related to Cpn tissue tropism and pathogenicity. We have sequenced the genomes of … WebDec 7, 2010 · Chlamydia trachomatis is spread by close social contact or sexual activity. ... Recombination in the ompA gene but not the omcB gene of Chlamydia contributes to serovar-specific differences in tissue tropism, immune surveillance, and persistence of the organism. J Bacteriol. portland or zoning

Genomic Analysis of MSM Rectal Chlamydia trachomatis

Chlamydial eye infections: Current perspectives - PubMed

WebDec 6, 2024 · Screening and diagnosis of chlamydia is relatively simple. Tests include: A urine test. A sample of your urine is analyzed in the laboratory for presence of this infection. A swab. For women, your doctor takes a swab of the discharge from your cervix for culture or antigen testing for chlamydia. This can be done during a routine Pap test. WebMay 17, 2013 · Despite the great diversity in disease, tissue tropism, and species specificity, the sequenced genomes of chlamydiae display a very high degree of synteny and sequence similarity. ... Hughes S, Belland RJ, et al. (2002) Molecular basis defining human Chlamydia trachomatis tissue tropism. A possible role for tryptophan … portland or. real estateWebNov 17, 2024 · 3 Altmetric. Metrics. Chlamydia is the most common sexually transmitted bacterial infection in humans but is often asymptomatic. Left untreated, chlamydia infection can lead to serious ... portland orange nails

"WebChlamydia trachomatis is an obligate intracellular bacterium that causes the sexually transmitted disease chlamydia. When this bacterium was first discovered, it was classified as a virus. ... has a remarkably broad tropism? CMV can infect connective tissue cells and parenchymal cells of virtually any organ. " - Chlamydia trachomatis tissue tropism

Chlamydia trachomatis tissue tropism

Genomic factors related to tissue tropism in Chlamydia …

WebNational Center for Biotechnology Information WebDec 14, 2024 · Chlamydia trachomatis is the leading cause of preventable blindness and the most common bacterial sexually transmitted infection. Different strains are associated with ocular or urogenital infections, and a …

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WebDec 6, 2024 · Early-stage Chlamydia trachomatis infections often cause few or no signs and symptoms. Even when signs and symptoms occur, they're often mild, making them … WebApr 10, 2012 · Results. A comparison of the genome of the avian Chlamydia psittaci isolate 6BC with the genomes of other chlamydial species, C. trachomatis, C. muridarum, C. pneumoniae, C. abortus, C. felis and C. caviae, revealed a high level of sequence conservation and synteny across taxa, with the major exception of the human pathogen …

WebAug 26, 2014 · No indication for tissue tropism in urogenital and anorectal Chlamydia trachomatis infections using high-resolution multilocus sequence typing BMC … WebJul 19, 2013 · Chlamydia trachomatis maintain a conserved plasmid, which is a primary regulator of chromosomal genes, but there is no experimental evidences associating it with the strains’ differential tissue tropism (ocular and genital mucosae, and lymph nodes). We investigated if the number of plasmids per strain correlate with expression profiles of …

WebChlamydia are obligate intracellular bacteria, characterized by a unique biphasic developmental cycle. Specific interactions with the host cell are crucial for the bacteria’s survival and amplification because of the reduced chlamydial genome. At the start of infection, pathogen-host interactions are set in place in order for Chlamydia to enter the … WebApr 7, 2015 · Chlamydia are obligate intracellular bacteria known to infect not only humans, but also reptiles, amoebae, fish and mammals [].Beside C. trachomatis and C. psittaci, C. pneumoniae (Cpn) is the third chlamydial species with human pathogenic potential, showing the highest infection and seropositivity rates (>70%) amongst them at the age of 65 …

WebNov 9, 2024 · Chlamydia trachomatis is the most prevalent sexually transmitted bacterium worldwide and the causative agent of trachoma. Its strains are classified …

WebApr 13, 2024 · Hence antibiotic that tackles the rectal Chlamydia trachomatis is the need of the hour . For the same STI, same antimicrobial or same regimen of dosing might not be the answer for different sites of infection in the body. ... Fehlner-Gardiner C et al. Molecular basis defining human Chlamydia trachomatis tissue tropism: A possible role for ... portland ore snowWebDec 4, 2024 · Chlamydia trachomatis is a major health burden worldwide in humans. The two C. trachomatis biovars show large differences in disease severity and tissue tropism despite less than 1% genetic ... optimal synonymerWebApr 1, 2014 · The Chlamydiaceae are a family of obligate intracellular bacteria characterized by a unique biphasic developmental cycle. It encompasses the single genus Chlamydia, which involves nine species that affect a wide range of vertebral hosts, causing infections with serious impact on human health (mainly due to Chlamydia trachomatis infections) … portland or zoo pricesWebEnter the email address you signed up with and we'll email you a reset link. portland or. road conditionsWebMar 11, 2012 · trachomatis diversity showed greater exchange between strains with tropism for the same site or tissue, which correlates with the majority of reports of mixed infections 43,44,45,46,47. However ... optimal systems distribution incWebsequencing and the analysis of tissue-tropism-associated genes located in the so-called plasticity zone of the genome [6–9]. In Spain, infection by C. trachomatis was included in the Notiﬁable ... portland orange theoryWebJul 26, 2002 · Curiously, the 15 different C. trachomatis serovars exhibit an extraordinary specificity in tissue tropism. For example, serovars A, B, Ba, and C are pathogens of the … optimal support stockport