Definition of lipophilic
Webhaving an affinity for lipids. Test prep from the experts. Boost your test score with programs developed by Vocabulary.com’s experts. WebCommercial honeycomb foundation, made by pressing beeswax between patterned metal rollers. Waxes are a diverse class of organic compounds that are lipophilic, malleable solids near ambient temperatures. They …
Definition of lipophilic
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WebOther articles where lipophilicity is discussed: surfactant: hydrophilic (water-soluble) and partly lipophilic (soluble in lipids, or oils). It concentrates at the interfaces between bodies or droplets of water and those of oil, or lipids, … WebAug 7, 2012 · Since lipophilicity is a key determinant in BBB permeability, lipidization, that is, conversion of the drug moiety into a more lipophilic form by the insertion of …
WebLipophilicity is an important physicochemical parameter to link membrane permeability and, drug absorption and distribution with the route of clearance (metabolic or renal). Measuring the compound lipophilicity is readily amenable to automation. WebLipophilic efficiency [1] ( LiPE ), sometimes referred to as ligand-lipophilicity efficiency ( LLE) is a parameter used in drug design and drug discovery to evaluate the quality of research compounds, linking potency and lipophilicity in an attempt to estimate druglikeness. [2] [3] For a given compound LiPE is defined as the pIC 50 (or pEC 50 ...
WebDefine lipophilic. lipophilic synonyms, lipophilic pronunciation, lipophilic translation, English dictionary definition of lipophilic. adj. Having an affinity for, tending to combine … Lipophilicity (from Greek λίπος "fat" and φίλος "friendly"), refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene. Such non-polar solvents are themselves lipophilic (translated as "fat-loving" or "fat-liking" ), and the axiom that "like dissolves like" generally holds true. Thus lipophilic substances tend to dissolve in other lipophilic substances, but hydrophilic ("water-loving") substances tend to dissolve in water and ot…
WebOther articles where lipophilicity is discussed: surfactant: hydrophilic (water-soluble) and partly lipophilic (soluble in lipids, or oils). It concentrates at the interfaces between bodies or droplets of water and …
WebLipophilic definition: having an affinity for lipids Meaning, pronunciation, translations and examples snaith chippy opening timesWebLipophilic definition: having an affinity for lipids Meaning, pronunciation, translations and examples rnase t1 thermo fisherWebJul 9, 2024 · While the terms hydrophobic and lipophilic are often used interchangeably, the two words don't mean the same thing. A lipophilic substance is "fat-loving." Most … rna sequencing and bioinformatics analysisWebDefinition: Lipophilic or 'lipid-loving' molecules are attracted to lipids. A substance is lipophilic if it is able to dissolve much more easily in lipid (a class of oily organic … rna-seq tool browser splicing moues brainWebMar 2, 2010 · The volume of distribution does not necessarily correspond to any specific physiologic volume or space. Drugs such as highly water-soluble compounds, which are confined intravascularly, have a small volume of distribution (approximately equal to intravascular volume), whereas lipophilic drugs that distribute to tissues have a large … snaith library opening timesWebdefinition measure of... P; balance between lipophilicity and hydrophilicity of a compound in the un-ionized form; measure of the relative affinity of the compound for lipids (specifically, n-octanol) as compared to water To determine the partition coefficient, one would dissolve the compound in question in a container with n-octanol and water. snaith iplWebThe use of PTHF, commercially available in a variety of molecular weights, enables better tuning of the length of the hydrophobic fragment in macromolecules, while the presence of PEG chains allows direct comparison of AIPEs-1 and AIPEs-2 in terms of the effect of macromolecular composition on micellization and other colloidal properties. snaithing grange sheffield