H2s tfeb
WebFeb 17, 2024 · TFEB promotes fatty acid oxidation in mitochondria and peroxisomes and inhibits fatty acid biosynthesis. Strikingly, TFEB action is a result of the different fatty acid types and duration of exposure to exogenous fatty acids in murine cardiomyocytes (Trivedi et al., 2024). TFEB content is decreased in a concentration- and time-dependent manner ... WebJan 29, 2024 · Autophagy. 2024 Jan 28:1-18. doi: 10.1080/15548627.2024.2026097. Online ahead of print.ABSTRACTVascular smooth muscle cells (VSMCs) contribute to plaque …
H2s tfeb
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WebApr 27, 2024 · Over-TFEB attenuates mitochondrial dysfunction and apoptosis in cisplatin-treated HK2 cells. ... Yuan Y, Zhu L, Li L, Liu J, Chen Y, Cheng J. et al. S-Sulfhydration …
WebHydrogen Sulfide is an extremely toxic and irritating gas. Free hydrogen sulfide in the blood reduces its oxygen-carrying capacity, thereby depressing the nervous system. … WebSilencing of TFEB partially abolishes the protective effects of trehalose in cisplatin-treated HK2 cells. HK2 cells were transfected with control siRNA (sicon) or TFEB siRNA (sitfeb) …
WebJul 21, 2024 · TFEBdb is a unique resource for those interested in understanding the effect of TFEB on a set of genes of interest. The database offers an intuitive interface and results are displayed in an easy-to-interpret format offering information on the expression changes following inducible over-expression, knock-down and knock-out of TFEB across cell lines … WebPubMed
WebJan 29, 2024 · Autophagy. 2024 Jan 28:1-18. doi: 10.1080/15548627.2024.2026097. Online ahead of print.ABSTRACTVascular smooth muscle cells (VSMCs) contribute to plaque stability. VSMCs are also a major source of CTH (cystathionine gamma-lyase)-hydrogen sulfide (H2S), a protective gasotransmitter in atherosclerosis. However, the role of …
WebMay 1, 2024 · Hydrogen sulfide (H2S), oxygen and glucose deprivation: 98-105 [84] MIR216A: HUVECs: BECN1 and ATG5: ox-LDL: N.D. [78] MIR30A: Cardiomyocytes: … dusko savanovic pesicWebFeb 4, 2024 · TFEB in Alzheimer's disease: From molecular mechanisms to therapeutic implications. Gu Z, Cao H, Zuo C, Huang Y, Miao J, Song Y, Yang Y, Zhu L ... Vascular smooth muscle cell-derived hydrogen sulfide promotes atherosclerotic plaque stability via TFEB (transcription factor EB)-mediated autophagy. Chen Z, Ouyang C, Zhang H, Gu … rebijutraWebMay 26, 2011 · RNA interference (RNAi) of TFEB in HeLa cells resulted in decreased levels of LC3-II both in normal and starved conditions, in either the presence or absence of bafilomycin (Fig. 1, C and D).The decrease of LC3-II correlated with the levels of TFEB down-regulation achieved by the different RNAi oligomers (fig. S4, C and D). These gain- … dusko tadic ajaxWebTFEB is a master gene for lysosomal biogenesis. [7] It encodes a transcription factor that coordinates expression of lysosomal hydrolases, membrane proteins and genes involved in autophagy. [7] [8] Upon nutrient depletion and under aberrant lysosomal storage conditions such as in lysosomal storage diseases, TFEB translocates from the cytoplasm ... rebillon mjpmWebNov 1, 2024 · TFEB belongs to the microphthalmia-transcription factor E (MiT/TFE) subfamily of basic helix–loop–helix factors and is a key regulator of the autophagy-lysosome pathway [13], [14]. Normally, TFEB is located in the cytosol and on the lysosome surface where it interacts with mTOR in an inactive phosphorylated form. rebika bijukchheWebDec 6, 2024 · TFEB and TFE3 belong to the MiTF-TFE family of basic helix-loop-helix leucine zipper (bHLH-LZ) transcription factors and have been well characterized as master regulators of the autophagy-lysosome pathway in response to starvation (Martina et al., 2014; Sardiello et al., 2009; Settembre et al., 2011).Under nutrient poor conditions, … re bioWebHydrogen sulfide (H 2 S) is an important gaseous signaling molecule that serves many important regulatory roles in physiological and pathophysiological conditions. H 2 S … re bike price list