High volume disease

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August undefined, 2024

WebA total of 57% of patients had a high metastatic burden and 60% of patients received docetaxel. The median follow-up for the ADT + docetaxel (n = 355) and the ADT + docetaxel + abiraterone (n = 355) was 36 months. The median time to discontinuation of abiraterone in the abiraterone group was 31.4 months. Symptoms of hypervolemia range in severity for each person and could include: 1. Swellingin an area of your body, most often your arms and legs, where it appears … See more Several factors could cause hypervolemia including too much salt in your body, an underlying condition or hormonal changes. See more Your kidneys help your body remove excess fluid through your urinary system, which leaves your body as pee (urine). Your kidneys function to balance the amount … See more

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WebJul 1, 2024 · Disease volume was classified as high volume (≥4 bone metastases or visceral metastases) versus low volume. Results: Among 424 patients (88% white), 213 (50%) had high-volume disease and 211 (50%) had low-volume disease, 275 (65%) had de novo metastatic disease, and 149 (35%) had metastatic recurrence of nonmetastatic disease. WebApr 12, 2024 · Docetaxel plus ADT should be offered to patients with metastatic noncastrate prostate cancer with high-volume disease (four or more bone metastases, one or more of which is outside of the spine or pelvis, and/or the presence of any visceral disease) who are candidates for chemotherapy but are unwilling or unable to receive triplet therapy. ... how many calories does stationary bike burn

Abiraterone acetate plus prednisone in patients with newly …

WebDefinition of high and low volume, and risk in CHAARTED [54-56] and LATITIDE [57] based upon imaging with bone scan and CT scan. Source publication EAU-EANM-ESTRO-ESUR … WebDec 22, 2024 · Case: A 73-Year-Old Man With Biochemical Recurrence of Prostate Cancer and Metastatic Castration-sensitive High-volume Disease. January 2024. Initial … WebMeaning of high volume. What does high volume mean? Information and translations of high volume in the most comprehensive dictionary definitions resource on the web. how many calories does sperm have

Definitions of disease burden across the spectrum of metastatic castra…

Case 2: High-Volume Versus Low-Volume Metastatic CSPC

WebHigh CCI should alert providers to increased probability of major complications, and warrant vigilant management after CUTE. Surgeon volume was inversely related to major postoperative complications. Perioperative Complications and Mortality in Patients with Urothelial Carcinoma and End-Stage Renal Disease Undergoing One-Stage Complete … WebJan 11, 2024 · High-volume disease per CHAARTED criteria was defined as the presence of visceral metastasis or ≥4 bone lesions with ≥1 beyond the vertebral bodies and pelvis; others were defined as low-volume... how many calories does sprite haveWebApr 15, 2024 · Background The long-term excessive intake of exogenous cholesterol can lead to abnormally elevated blood lipid levels and induce cardiovascular and cerebrovascular diseases. However, the influence and relevance of exogenous cholesterol on plasma cholesterol components were still unclear, and the influence on intestinal lipid … high ramp

"WebSep 5, 2024 · The CHART trial only recruited patients with high-volume disease on conventional imaging defined as per the CHAARTED study, and did not detail whether patients had de novo or metachronous metastatic disease. " - High volume disease

High volume disease

Treating Prostate Cancer with Low-Volume Metastatic Disease

WebDec 30, 2024 · People with high platelet levels often don't have signs or symptoms. When symptoms occur, they're often related to blood clots. Examples include: Headache. …

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WebIn the first part, abiraterone ranked first for high-volume mHSPC. Conversely, enzalutamide ranked first for low-volume mHSPC. In the second part, abiraterone treatment in high … WebIn stroke patients with large-vessel disease, high on-treatment platelet reactivity is associated with a larger extent of acute ischemic focus and chronic ischemic lesions in …

WebApr 27, 2024 · We’re used to thinking about prostate cancer as high volume vs low volume. We didn’t see that in this trial. ... M1b, and M1c. Visceral disease represented about 17%, … WebMar 2, 2024 · Summary of relative and absolute risks for mixed treatment comparisons derived from frequentist network meta-analysis using 4 levels of certainty: high (further research very unlikely to change confidence in the estimate of effect), moderate (further research likely to have important association with confidence in estimate of effect and …

WebApr 12, 2024 · In our post-hoc exploratory analysis of the high-volume disease subgroup (n=487 in the abiraterone acetate plus prednisone and 468 in the placebo group), median overall survival was 49·7 months (95% CI 43·2–55·4) with abiraterone acetate plus prednisone compared with 33·3 months (30·2–36·7) with placebos, with an HR for death … WebApr 10, 2024 · High-volume disease was defined as presence of visceral metastases and/or ≥ four bone metastases with at least one outside of the vertebral column and pelvis. …

WebJul 21, 2024 · High-volume metastatic burden was defined as per the CHAARTED study as the presence of visceral metastases or at least four bone lesions, with one beyond the vertebral bodies and pelvis. 10 In the docetaxel sub-population, after a median follow-up of 3.5 years, the co-primary endpoint of rPFS was 4.5 years and 2.0 years in the SOC plus …

WebNov 19, 2024 · How many patients present with metastatic disease? This high volume/low volume has a certain arbitrariness to it, depending on the imaging you use. Then we have … how many calories does stretching yoga burnWebJul 1, 2024 · Results: The number of patients with CHAARTED low-volume and high-volume diseases was 178 (33.5%) and 354 (66.5%), respectively. On the contrary, the number of patients with LATITUDE low-risk and high-risk diseases … high ranch bookcase railing dividerWebSep 2, 2014 · In the 520 patients who had high-extent disease, treatment with ADT plus docetaxel had a median overall survival of 49.2 months versus 32.2 in the ADT-only group — a difference of 17 months. high ranch bathroom designsWebJul 2, 2024 · The patients with CHAARTED high-volume disease or LATITUDE high-risk disease showed a shorter CRPC-free survival and a shorter OS than those in the … how many calories does steak haveWebFeb 25, 2024 · There was a smaller effect on overall survival in patients with high-volume disease, those planned for early docetaxel, and those on antiresorptive bone therapy. These subgroup analyses are limited. The amount of follow-up has been not quite as long. We didn’t have as many deaths for the overall survival cohort. high ranchWebAbout 47% of American adults have high blood pressure, according to the U.S. Centers for Disease Control and Prevention. About half of men and 44% of women have high blood … how many calories does stretching burnWebFeb 9, 2024 · PSA is a protein made by both normal and cancerous cells in your prostate. A higher PSA level in your blood is associated with an increased risk of developing prostate … how many calories does sugar have