Phf14

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August undefined, 2024

Web1. dec 2024 · 3.2. PHF14 is needed for the proliferation of GC B cells. In the further analysis, we explored the reason for decreased GC formation and revealed a skew in dark zone and … WebIn addition, PHF14 suppressed the expression of Cdkn1a (p21) though regulating the level of H3K4me3 to control the proliferation of GC B cells. Collectively, our data suggest that …

PHF14 is required for germinal center B cell development

PHF14 (PHD Finger Protein 14) is a Protein Coding gene. Diseases associated with PHF14 include Ceroid Lipofuscinosis, Neuronal, 9 and Dandy-Walker Syndrome . An important paralog of this gene is BRD1 . Web27. nov 2024 · PHF14, a member of the PHD finger protein family, is coded by a highly conserved gene found in the 19p13.2 chromosomal region . PHF14 has been described as a modulator for mesenchymal cells proliferation in alveolar tissues [20, 21], as well as a novel hypoxia-sensitive epigenetic regulator in cell proliferation . However, the biological ... geraghty creative

Anti-PHF14 Antibodies Invitrogen - Thermo Fisher Scientific

WebPHF14 is highly conserved from C. elegans to humans and is considered as a transcriptional regulator of target gene expression. PHF14 has been identified as a regulator of … WebAntibodies that detect PHF14 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and … WebPHF14 is upregulated in a folic acid-induced kidney fibrosis mouse model. To explore the expres-sion profile of PHF14 after pro-fibrotic insults in mice, a folic acid-induced kidney fibrosis mouse ... christie\\u0027s human resources new york

Upregulation of PHF14 in lung cancer is significantly associated …

PHF14 is required for germinal center B cell development

WebIn addition, PHF14 suppressed the expression of Cdkn1a (p21) though regulating the level of H3K4me3 to control the proliferation of GC B cells. Collectively, our data suggest that PHF14 plays an important role in the process of germinal center formation by regulating GC B cell proliferation in spleen. WebPrestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution. Synonym (s): Anti-PHD finger protein 14 antibody produced in … christie\u0027s indiana auctionWebPHF14. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. geraghty creative llc

"Web1. dec 2024 · PHF14 regulates the proliferation of GC B cells by p21. The GC B cells from the spleen of PHF14 GCB KO and PHF14 GCB KO mice 7 d after SRBC immunization were sorted and analyzed by RNA-seq. We found increased mRNA of Cdkn1a (p21) in the GC B cells from PHF14 GCB KO mice than the PHF14 GCB WT mice ( Fig. 4 A). " - Phf14

Phf14

Web10. apr 2024 · PHF14 plays an oncogenic role in CRC, and the mutation rate of PHF14 in CRC patients was as high as 18%. • PHF14 interacts with KIF4A contributes to the formation … WebPHF14 Promotes Cell Proliferation and Migration through the AKT and ERK1/2 Pathways in Gastric Cancer Cells. Study revealed that miR-590 was shown to directly target PHF14 …

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Webphf14全长含有3-4个phd锌指结构域。作为一类表观调控因子，phf14在胚胎发育，癌症发生和组织稳态维持等过程中均发挥着重要作用。例如，纯合敲除phf14的小鼠在出生几个小 … Web3. jan 2024 · Abstract. PHF14 is a newly identified regulator of mesenchyme growth in embryonic tissues. Previous studies have shown that phf14-null mutants die just after …

Web7. okt 2024 · 7D86, 7D87, 7D8A. PubMed Abstract: Histone recognition constitutes a key epigenetic mechanism in gene regulation and cell fate decision. PHF14 is a conserved multi-PHD finger protein that has been implicated in organ development, tissue homeostasis, and tumorigenesis. Here we show that PHF14 reads unmodified histone H3 (1-34) through an ... Web12. okt 2024 · The PHF14 complex rapidly assembles at DNA damage sites and binds to DNA through HMG20A. The PHF14 complex forms DNA-containing phase separated …

WebPHF14: 42: Sequence caution The sequence BAA34503.2 differs from that shown. Reason: Erroneous initiation Extended N-terminus. Curated. Features. Showing features for alternative sequence, compositional bias, sequence conflict. Type. ID Position(s) Description; Alternative sequence: VSP_061645: 1-300: WebPHF14 Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, PHF14 Genome Browser, PHF14 References PHF14 - Explore an overview of PHF14, with a …

Web1. aug 2013 · Three transcripts of PHF14 in human cell lines were identified by reverse transcriptase polymerase chain reaction. Two isoforms of PHF14 (PHF14α and PHF14β) …

WebPHF14 is a member of the PHD finger protein family that serves as a chromatin-binding protein. It contains four putative PHD fingers, two coiled-coil regions, and four zinc fingers. PHF14 is highly conserved from C. elegans to humans and is considered as a transcriptional regulator of target gene expression. christie\u0027s in coral gablesWebPHF14, PHD finger protein 14 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog PHF14, PHD finger protein 14. Links HGNC:22203. NCBI Gene ID: 9678. neXtProt AC: NX_O94880. UniProt: O94880. Chr Location 7p21.3 ... geraghty dougherty \\u0026 stockmanWeb28. feb 2024 · Given that SIRT1 is a protein deacetylase, we tested whether PHF14 could favour protein acetylation. Indeed, PHF14 and associated proteins were already proposed to function by counteracting the function of the repressive LSD1-CoREST complex, which contains histone deacetylases along the H3K4 demethylase (Garay et al., 2016; Wynder et … geraghty dentist wexfordWeb10. apr 2024 · In vitro, PHF14 was significantly expressed in patient tissues and in various CRC cell lines, and its expression was closely associated with cell proliferation and … geraghty dougherty and edwardsWebA Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances. The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. geraghty dougherty \u0026 stockmanWebUsing a knockdown screen, Kitagawa et al. (2012) identified Phf14 as a regulator of proliferation in MEFs. Using a proteomic approach with coimmunoprecipitation, Huang et … christie\u0027s in new yorkWeb2. apr 2024 · Author Correction: PHF14: an innate inhibitor against the progression of renal fibrosis following folic acid-induced kidney injury Sci Rep . 2024 Apr 2;10(1):6036. doi: 10.1038/s41598-020-62765-7. geraghty butchers stratford garden centre