Sialic acid acetylesterase
WebEsterases and autoimmunity: the sialic acid acetylesterase pathway and the regulation of peripheral B cell tolerance Shiv Pillai, Annaiah Cariappa and Stephan P. Pirnie Cancer … http://www.cazy.org/Carbohydrate-Esterases
Sialic acid acetylesterase
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WebNov 22, 2024 · Functionally defective germline variants of sialic acid acetylesterase in autoimmunity. Nature. Jul 2010 Functionally defective, rare, non-synonymous, germ-line, … WebApr 11, 2024 · In contrast, the previously described sialic acid regulon known as sialoregulon (i.e. nanRATEK-yhcH, nanXY, and nanCMS) was not associated with any host species. In …
WebMar 3, 2024 · The sialic acid concentration in culture supernatants was consistent with the growth profiles of pneumococcal strains. ... Rott R, Klenk HD, Muller HP, Shukla AK, … The enzyme sialate O-acetylesterase (EC 3.1.1.53) catalyzes the reaction ... "High performance liquid chromatography of enzymes of sialic acid metabolism". Hoppe-Seyler's Z. Physiol. Chem. 363: 1039–1040. This page was last edited on 16 August 2024, at 15:45 (UTC). Text is available under the Creative … See more The enzyme sialate O-acetylesterase (EC 3.1.1.53) catalyzes the reaction N-acetyl-O-acetylneuraminate + H2O = N-acetylneuraminate + acetate In human it is encoded by the SIAE gene located on See more The SIAE gene contains 15 exons and expresses a protein that is approximately 56 kDa in size. It is known to be expressed in the adult See more SIAE activity negatively regulates B lymphocyte antigen receptor signalling and is required for the maintenance of immunological tolerance. It down-regulates B lymphocyte antigen receptor signaling (involving CD22), and is required for See more Genetic defects in SIAE have been associated with multiple autoimmune diseases. Loss of function mutations in SIAE are much more frequently found in humans with See more
WebMar 5, 2024 · This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune … WebAcetyl esterase, sialate-O-acetylesterase. The LudgerZyme Acetyl Esterase Kit removes 9-, 8- and 7-O-acetyl groups from released sialic acids, released glycans or glycoproteins. It …
WebOct 1, 2024 · Sialic acid acetylesterase (SIAE) removes acetyl moieties from the carbon 9 and 4 hydroxyl groups of sialic acid and recently a debate has been opened on its …
WebEnter the email address you signed up with and we'll email you a reset link. the pe tutorWebThis cytosolic sialic acid-specific O-acetylesterase appears to be involved in the "recycling" of O-acetylated sialic acid molecules. Thus, esterase D may be the first nonspecific … the petusis cultWebSep 21, 2009 · Figure 1 The SIAE (sialic acid acetylesterase)-Siglec pathway for inhibitory signaling. (i) The B cell receptor (BCR) and other membrane glycoproteins can have … the petunia twinsWebA sialic acid-specific O-acetylesterase in human erythrocytes: possible identity with esterase D, the genetic marker of retinoblastomas and Wilson disease. by A Varki, E Muchmore, S … sicily holidays for singlesWebSialate 9 (4)-O-acetylesterases (EC 3.1.1.53) have been isolated from equine liver, bovine brain and influenza C virus. In this latter case, the esterase represents the receptor … the petunia carnageWebJun 19, 2024 · Sialic acids are nine-carbon sugars that frequently cap glycans at the cell surface in cells of vertebrates as well as cells of certain types of invertebrates and … the petuniaWebSep 28, 2024 · SIAE sialic acid acetylesterase Gene ID: 54414, updated on 28-Sep-2024 Gene type: protein coding Also known as: ... This gene encodes an enzyme which … sicily homes for sale 1 euro